Open AccessElaboration of the bischofite eye drops using the biopharmaceutical criteria
Author(s) -
Б. Б. Сысуев,
Ye. B. Sysuev,
I. Yu. Mitrofanova
Publication year - 2011
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2011-5-162-166
Subject(s) - biopharmaceutical , elaboration , process engineering , macro , composition (language) , computer science , analytic hierarchy process , biochemical engineering , engineering drawing , mathematics , manufacturing engineering , engineering , operations research , microbiology and biotechnology , humanities , philosophy , linguistics , biology , programming language
Our research is of theoretical and practical importance and aims at the development of ophthalmological dosage form comprising mineral component (bischofite). It is mineral complex consisting of 96% magnesium chloride with macro- and microelements. Having carried out complex physicochemical and biopharmaceutical researches in vitro, we developed composition and technology of 10% bischofite solution in the form of eye drops. After is one of the perspective tools in technological researches. After using of the analytic hierarchy process by T. Saaty the optimal eye drops composition was selected according to all chosen criteria for this pharmaceutical form.