Open AccessExperimental histochrome's effect on the renal excretory function
Author(s) -
O. S. Talalayeva,
A. Yu. Zharikov,
S. A. Fedoreyev,
Ya. F. Zverev,
V. M. Bryukhanov,
Nataliya P. Mishchenko,
В. В. Лампатов
Publication year - 2011
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2011-5-101-105
Subject(s) - excretory system , diuretic , potassium , sodium , renal function , chemistry , excretion , kidney , endocrinology , urology , medicine , pharmacology , zoology , biology , organic chemistry
The aim of present investigation was to establish possible histochrome's effect on the renal excretory function. During 10 days was being administrated histochrome by subcutaneous injections in dose 10 mg/kg. Every 2 days was being detected daily renal excretions of water, creatinin, sodium and potassium. Long-term histochrome's administration was followed by a fivefold increasing of water excretion and comparable amplification of creatinin. Sodium's and potassium's excretions were increasing to a lesser degree. The revealed histochrome's diuretic effect qualitatively reminds action of diuretic plants, but quantitatively it was compared with thiazid's one.