Open AccessThe experience of oxalate nephrolithiasis therapy by sodium pyrophosphate in experiment
Author(s) -
Жариков Александр Юрьевич,
Зверев Яков Федорович,
Лампатов Вячеслав Витальевич,
Брюханов Валерий Михайлович,
Азарова Ольга Васильевна,
Талалаева Ольга Сергеевна,
Кудинов Алексей Владимирович,
Мотин Юрий Григорьевич
Publication year - 2011
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2011-1-32-37
Subject(s) - pyrophosphate , oxalate , sodium , sodium oxalate , chemistry , medicine , urology , enzyme , endocrinology , biochemistry , inorganic chemistry , organic chemistry
The aim of the investigation was studying sodium pyrophosphate’s effect on experimental oxalate nephrolithiasis. Experimental nephrolithiasis modeling by using of 1% ethylenglycole’s solution as a drink for rats during 6 weeks. First group was control. In the second group since the third week was being administrated sodium pyrophosphate in dose 2 g/kg. Was detecting parameters of kidney’s function, markers enzymes activity, was carried out morphological researches. It was concluded that sodium pyrophosphate’s therapy reduce experimental oxalate nephrolithiasis.