Open AccessThe genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
Author(s) -
О. В. Воронкова,
O. I. Urazova,
Р. Р. Хасанова,
V. V. Novitsky,
Ye. G. Churina,
I. O. Naslednikova,
O. V. Filinyuk,
V. A. Serebryakova,
Yu. V. Kolobovnikova
Publication year - 2011
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2011-1-12-17
Subject(s) - tuberculosis , mycobacterium tuberculosis , medicine , pulmonary tuberculosis , population , virology , microbiology and biotechnology , biology , pathology , environmental health
The results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulating in Tomsk and the Tomsk Region, and causing acute progressive destructive pulmonary tuberculosis, 19% show multi drag resistance. Beijing family strains make 27% from the general population, have a high clusterization index (74%), level of their multi drag resistance in 3 times exceeds that at «not Beijing» strains for which the share of clustering strains makes 11%.