Open AccessRole of cytoskeleton in formation of airway muscle activity in the presence of nanosized magnetite
Author(s) -
Т. Н. Зайцева,
А. В. Носарев,
Ye. Yu. Diyakova,
Л. В. Капилевич,
B. G. Ageyev,
L. N. Ogorodova,
A. A. Magayeva,
О. Г. Терехова,
V. I. Iteen
Publication year - 2010
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2010-6-41-43
Subject(s) - nocodazole , cytoskeleton , histaminergic , colchicine , cholinergic , histamine , chemistry , biophysics , microbiology and biotechnology , medicine , biology , biochemistry , cell
The mechanographic method was used to study the influence of iron oxide nano-powder on airway muscle activity in guinea pigs. Under the action of nanomaterial on isolated segments, amplitudes of cholinergic and histaminergic contractile reactions increased. The pre-processing of cytoskeleton by colchicines and nocodazole disintegrators led to an increase in the mechanical stress of segments under the action of carbacholine and histamine.