Open AccessEfficiency of application of antioxidants from group sterically hindered phenols by retina photodegradation
Author(s) -
А. А. Жданкина,
Plotnikov Mb,
George Armand Robert Kon,
И. С. Иванов,
Ye. Yu. Varakuta,
А. В. Кучин,
I. Yu. Chukicheva,
С. В. Логвинов
Publication year - 2010
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2010-5-32-38
Subject(s) - retina , steric effects , photodegradation , phenols , chemistry , lesion , retinal , pigment , medicine , biochemistry , biology , organic chemistry , pathology , neuroscience , photocatalysis , catalysis
Renoprotective effect of antioxidants from group sterically hindered phenols (thiophane, dibornol) in white nondescript male rats (n = 55) subjected to influence of light intensity level 6 000 lx during 6 h was demonstrated. Course intragastric administration of thiophane limited of destructive changes in the retina, but didn’t bring to disappearance of lesion focuses. Dibornol prevented progression of local changes in the retina, contributed to decrease destruction of neurosensory cells, pigment epithelium and neurons of internal layer.