Open AccessThe role of γδТ- and NK-сells in immune response
Author(s) -
Ye. G. Churina,
О. И. Уразова,
V. V. Novitsky,
И. О. Наследникова,
О. В. Воронкова
Publication year - 2010
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2010-5-138-142
Subject(s) - immune system , effector , biology , immunology , microbiology and biotechnology
The article presents up-to-date literature data on the role of γδТ-cells and different NK-cells subpopulations in the immune response. Their origin, immunophenotypes, range of secreted cytokines as well as effector functions and factors having stimulating and inhibitory effect on γδТ- and NK-cells are described. Mechanisms of antibacterial action of this type of cells are analyzed.