Open AccessChelating agents action on rat prostate
Author(s) -
Yu. V. Yeschenko,
V. V. Novitsky,
В. Д. Бовт,
V. A. Yeschenko,
О. И. Уразова
Publication year - 2010
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2010-3-65-67
Subject(s) - dithizone , zinc , chelation , prostate , chemistry , phase (matter) , nuclear chemistry , medicine , inorganic chemistry , organic chemistry , cancer
It was shown in experiments on rats, that dithizone induced zinc deficiency in prostate cells. Three phase type of fluctuations of cytochemically detected zinc concentration was observed in the cells: phase of primary decrease, phase of temporary partial restoration and the phase of secondary decrease. Sodium diethyldithiocarbamate unlike to dithizone didn’t induce damage of cells and secondary decrease zinc content in its.