Open AccessRole of stilbens in mechanisms hepatoprotective properties of polyphenols Maackia amurensis
Author(s) -
В. С. Чучалин,
A. V. Ratkin,
Е. В. Ратькин,
В. Н. Фролов,
В. В. Иванов,
С. А. Федореев,
Victor P. Bulgakov,
С. С. Зоркальцев
Publication year - 2010
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2010-3-101-105
Subject(s) - polyphenol , chemistry , dimer , monomer , pharmacology , biochemistry , traditional medicine , antioxidant , biology , medicine , organic chemistry , polymer
For finding-out of a role monomer and dimer srilbens in realization hepatoprotective properties of polyphenols maakia amurensis activity of polyphenolic complexes from wood (Maksar), an extract of cellular culture maakia amurensis, and also monomer and dimer srilbens, allocated of a substance Maksar was investigated. Therapeutic efficiency of researched objects was estimated on their influence on survival rate of animals, morphological and biochemical parameters of a liver and wheys of blood of rats with an experimental СCl4-hepatites. It was established, that hepatoprotective influence of Maksar and an extract of cellular culture maakia amurensis is caused by presence of the sums isoflavonoids in their structure. Monomer and dimer srilbens do not show therapeutic activity at an experimental toxic hepatites.