Open AccessThe role of cytokines in the pathogenesis of autoimmune diabetes, immune intervention issues
Author(s) -
Ye. B. Кravets,
Т. В. Саприна,
Ф. Э. Лазаренко,
Т. С. Прохоренко,
N. V. Ryazantsevа
Publication year - 2010
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2010-1-76-83
Subject(s) - autoimmune diabetes , diabetes mellitus , immunology , medicine , immune system , pathogenesis , autoimmunity , autoimmune disease , intervention (counseling) , endocrinology , antibody , psychiatry
The review devotes to studying the role of cytokines in development of autoimmune diabetes mellitus, latent autoimmune diabetes in adults included. Therapeutic approaches to prevent the loss of endogenous insulin secretion are discussed. There is review of clinical trials of immunosuppressive agents and modulators of immune tolerance in autoimmune diabetes mellitus.