Open AccessHemostasis system condition and endothelium functions during various pathogenesis types of ischemic strokes in the acute and regenerative periods
Author(s) -
Е. Г. Смертина,
С. В. Прокопенко,
В.Г. Ионова,
М.М. Танашян,
В. В. Потылицина
Publication year - 2009
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2009-1(2)-72-77
Subject(s) - hemostasis , pathogenesis , medicine , endothelium , platelet , pathological , thrombosis , antithrombotic , cardiology , stroke (engine) , platelet activation , ischemic stroke , ischemia , mechanical engineering , engineering
It is revealed, that pathological changes in the plasmatic and platelets-vascular part of a hemostasis are expressed to a lesser degree in the acute period of the lacunar stroke in comparison with a nonlacunar stroke. Safety of antithrombotic properties of a vascular wall in the given subgroup is confirmed. Dis - tinctions in the hemostasis profile of various pathogenesis types of strokes disappear in the early regenerative period of stroke, lasting haemostatic activation with hyperfirinogenemia, and increase in markers of thrombosis, strengthening of spontaneous platelet’s aggregation, as well as increase of level of a marker endothelium dysfunction remains with the expressed decrease in reactance endothelium.