Open AccessAdhesion molecules and proinflammatory cytokines in cerebrospinal fluid of multiple sclerosis patients
Author(s) -
С. А. Ельчанинова,
И. В. Смагина,
В. А. Сидоренко,
Ю. Н. Личенко,
А. В. Поповцева,
А. С. Федянин
Publication year - 2009
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2009-1(2)-23-26
Subject(s) - multiple sclerosis , proinflammatory cytokine , exacerbation , cerebrospinal fluid , cell adhesion molecule , pathogenesis , tumor necrosis factor alpha , medicine , adhesion , interleukin , immunology , pathology , cytokine , inflammation , chemistry , organic chemistry
In liquor 30 multiple sclerosis patients with remittent kind of clinical course the concentration of cell-cell adhesion molecules (sPECAM-1, sVCAM-1) and tumor necrosis factor (TNF) α, not interleukin-1β, was higher during the period of exacerbation compared to the period of remission. These changes are supposed to display the activity of pathogenesis important processes multiple sclerosis in cerebral tissue of multiple sclerosis patients.