Open AccessThe results of epidemiological effectiveness study of Jodantipyrin as a drug for immediate prophylaxis of tick-borne encephalitis
Author(s) -
В. Н. Худолей,
Е. В. Замятина,
Elena A. Kropotkina,
Lyudmila Lukashova,
А. В. Лепёхин,
Г. А. Данчинова,
В. И. Злобин
Publication year - 2008
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2008-5-2-461-464
Subject(s) - medicine , encephalitis , tick borne encephalitis , drug , pharmacology , immunology , virus
Jodantipyrin is an antiviral medicament, inductor of endogenous interferon. It relates to the group of nonsteroidal antiinflammatory medicaments of pyrazolone derivative. The principal mechanism of Jodantipyrin antiviral effect is its ability to induce endogenous interferons of the 1 st and 2 nd types, what has been confirmed by the results of numerous and detailed preclinical and clinical trials. At the present time a long-term experience of this medicament application as a prophylactic agent in case of tick-borne encephalitis and data of postmarketing monitoring of the medicament safety have been accumulated. This experience confirms efficacy of the medicament in prophylaxis of tick-borne encephalitis.