Open AccessRole of blood plasma fatty acids in pathogenesis of stable anginapectoris
Author(s) -
В. В. Новицкий,
Р. С. Карпов,
С. В. Клименков,
А. Б. Салмина,
М. Ю. Котловский,
С. В. Машковская,
Д. А. Кириченко,
Р. А. Бутьянов,
А. П. Кускаев,
Evgeniya V. Bolshakova,
Ю. В. Котловский
Publication year - 2007
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2007-4-41-45
Subject(s) - fatty acid , medicine , pathogenesis , endocrinology , metabolism , chemistry , fatty acid metabolism , polyunsaturated fatty acid , biology , biochemistry
In men and women suffering from stable angina pectoris of 1-2 functional classes and aged from 35 to 69 years old, decrease of C 23:0 and increase of C 18:1(11) fatty acids was observed regardless of sex, the content of the rest fatty acids changed depending on patients sex. Correlation was found that metabolism of fatty acids in this pathology group depends on patients sex: men in the control group showed decrease in the sum of omega-3 fatty acids as well as in the omega-3/omega-6 fatty acid ratio, while women showed decrease of omega-6 fatty acids at the constant sum of omega-3 fatty acids. Regardless of sex, the presence of this pathology is accompanied with decrease in correlations between fatty acids, as the number of correlations between saturated fatty acids increases and the number of correlations between not saturated and saturated fatty aсids decreases. Change in correlations between not saturated fatty acids depends on sex. In the number of patients having supernormal fatty acid contents, no pronounced differences were found between men and women.