Open AccessThe condition of colonization resistance in surgical patientsearly after the surgery
Author(s) -
А. Б. Чеботарь,
M. V. Choubik,
Ye. P. Krasnozhenov,
G. Ts. Dambayev
Publication year - 2007
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2007-2-60-64
Subject(s) - colonization , colonisation resistance , surgical infections , immune system , organism , flora (microbiology) , biology , microbiology and biotechnology , medicine , immunology , bacteria , antibiotics , paleontology , genetics
We have examined one of the main components of the mechanism of purulent-inflammation complications in surgical patients. It is normal microflora which reflects the condition of colonization resistance of the organism which is a leading mechanism of opposition to hospital infections. We have established changes of microflora of different biotopes of the organism in dependence on pathologic focus localization and of the period after the surgery. Complex approach to the investigation of colonization resistance allowed to discover not only dysbiotic changes but disturbances of some immunological mechanisms of total and local anti- infectious protection in surgical patients. It is desirable to combine selective decontamination with taking drugs which normalize indigenous micro-flora of the host (special diets, growth stimulators of normal microflora representatives, eubiotics) and immune-stimulating therapy.