Open AccessFunctional activity of gdТ-cells in atopic dermatitis
Author(s) -
Ye. G. Chourina,
Vladimir V. Klimov
Publication year - 2006
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2006-2-137-140
Subject(s) - atopic dermatitis , concomitant , disease , immunity , medicine , immunology , stage (stratigraphy) , biology , immune system , paleontology
Functional activity of gdТ-cells in atopic dermatitis (AD) in dependence on the disease stage and concomitant pathology character was studied. We investigated 86 patients: 54 women and 32 men aged 17—50 years. AD patients revealed significant insufficiency of the cell immunity, the most marked of them being in gdТ-cells.The level of CD8aa did not differ practically but number of CD8ab-cells and NK-cells was decreased. Clinically, it manifested in continuously recurrent course of the disease with high risk of complications with joiningbacterial and viral infections.