Open AccessMolecular and cellular basis of pathogenesis of tick-borne encephalitis
Author(s) -
Р. Ф. Насырова,
N. V. Ryazantsevа,
N. G. Zhoukova,
А. П. Зима,
O. B. Zhoukova,
O. Ye. Chechina,
A. V. Lepyokhin,
N. Yu. Chasovskikh,
V. V. Novitsky
Publication year - 2006
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2006--42-51
Subject(s) - tick borne encephalitis , pathogenesis , encephalitis , biology , immune system , virus , immunology , virology , disease , tick , medicine , pathology
Main features of pathogenesis of tick-borne encephalitis virus’ persistense and outcome of the disease are determined by a complex xharacter of interaction between the virus and immune system of a patient. One of the main terms of pathogenetically im- portant virus activation is a low immune resistanse of an organism. The current article discusses role of modification of cellular dif- ferentiation, intercellular cooperation and cytogenetic instability of immunocytes as well as apoptosis as leading features of immu- nopathogenesis of tick-borne encephalitis.