Open AccessMaksar hepatoprotector is an effective corrector of prednisolone immunosuppressive action at experimental toxic hepatitis
Author(s) -
А. И. Венгеровский,
Л. М. Огородова,
Т. В. Перевозчикова
Publication year - 2003
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2003-3-25-30
Subject(s) - prednisolone , toxic hepatitis , spleen , medicine , hepatitis , glucocorticoid receptor , immunology , pharmacology , endocrinology , glucocorticoid
Polyphenol containing hepatoprotectors — maksar (complex of isoflavones and stilbenes of Far East plant — Maaсkia amurensis Rupr.et Maxim.) and legalon — during combined introduction with prednisolone to rats with chronic hepatitis, caused by tetrachloromethane, weaken the immunosuppressive action of glucocorticoid – augment the blood lymphocyte quantity, prevent the thymus atrophy, increase the blasts and antibody-forming cells content in spleen and the functional activity of with C 3b -receptors in peritoneal exudation.