Open AccessVariants of Epstein—Barr viral infection course in infectious mononucleosis nidus for the children
Author(s) -
А. П. Помогаева,
O. I. Galaktionova
Publication year - 2003
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2003-2-86-89
Subject(s) - mononucleosis , serology , virus , virology , epstein–barr virus , immunology , disease , immune system , infectious disease (medical specialty) , medicine , antibody , pathology
The aim of this investigation is to assess variants of Epstein—Barr viral infection course in infectious mononucleosis nidus. There have been examined 5 groups of preschool institutions, in each there was found 1 case of typical infectious mononucleosis caused by Epstein—Barr virus. Total number of children under observation was 67: 5 children with typical (clinical) infectious mononucleosis and 62 children being in contact under the disease. Analyses of life history, clinical examination, peripheral blood examination, serologic marker spectrum of EBV- and HIV-infections and factors of immune system cellular component have been made during investigation. It was found that 1 child in a contact group was absolutely healthy, 53 children were virus carriers and 8 children had atypical infectious mononucleosis. Upon the investigation results the formation of infectious mononucleosis nidus has been proved and their peculiarities have been found.