Open AccessCellular irinotecan resistance in colorectal cancer and overcoming irinotecan refractoriness through various combination trials including DNA methyltransferase inhibitors: a review
Author(s) -
Shogo Ozawa,
Toshitaka Miura,
Jun Terashima,
Wataru Habano
Publication year - 2021
Language(s) - English
DOI - 10.20517/cdr.2021.82
Subject(s) - irinotecan , cetuximab , colorectal cancer , cancer research , camptothecin , medicine , pharmacology , drug resistance , abcg2 , topoisomerase inhibitor , topoisomerase , biology , cancer , oncology , atp binding cassette transporter , genetics , transporter , gene , dna , biochemistry