Open AccessThe roles of the human ATP-binding cassette transporters P-glycoprotein and ABCG2 in multidrug resistance in cancer and at endogenous sites: future opportunities for structure-based drug design of inhibitors
Author(s) -
Jason Goebel,
Jean Chmielewski,
Christine A. Hrycyna
Publication year - 2021
Language(s) - English
DOI - 10.20517/cdr.2021.19
Subject(s) - abcg2 , atp binding cassette transporter , multiple drug resistance , p glycoprotein , pharmacology , transporter , drug resistance , efflux , drug , biology , cancer , cancer research , medicine , biochemistry , genetics , gene