Open AccessTAVI specific sex consideration
Author(s) -
Giulia Masiero,
Valeria Paradies,
Anna Franzone,
Bárbara Bellini,
Chiara De Biase,
Nicole Karam,
Francesca Sanguineti,
Hélène Eltchaninoff,
Chiara Fraccaro,
Alaide Chieffo
Publication year - 2022
Publication title -
mini-invasive surgery
Language(s) - English
Resource type - Journals
ISSN - 2574-1225
DOI - 10.20517/2574-1225.2021.104
Subject(s) - medicine , stenosis , percutaneous , epidemiology , presentation (obstetrics) , pathophysiology , sex characteristics , cardiology , surgery
The impact of sex on baseline characteristics and morphological and clinical presentation of degenerative aortic stenosis has been widely demonstrated but poorly understood. Moreover, differently from valve surgery, where patients were predominantly male, both sexes have been well represented in percutaneous treatment of aortic stenosis (AS), and women appeared to derive greater benefit with transfemoral aortic valve implantation (TAVI) compared to surgical treatment. This review focuses on sex-specific differences in epidemiology, pathophysiology, diagnostic issues, treatment options, and clinical outcomes of degenerative AS. Moreover, we evaluate how sex-based TAVI management, from device selection to procedural tricks, may affect outcomes.