Open AccessRole of locoregional therapies in the management of patients with hepatocellular carcinoma
Author(s) -
Janet Wui Cheung Kung,
Kkc Ng
Publication year - 2022
Publication title -
hepatoma research
Language(s) - English
Resource type - Journals
eISSN - 2454-2520
pISSN - 2394-5079
DOI - 10.20517/2394-5079.2021.138
Subject(s) - medicine , hepatocellular carcinoma , liver transplantation , milan criteria , stage (stratigraphy) , disease , cancer , curative treatment , liver cancer , hepatocellular cancer , surgery , oncology , transplantation , paleontology , biology
Hepatocellular carcinoma (HCC) was the sixth most common cancer and the third cause of cancer-related deaths worldwide in 2020. Liver resection and transplantation remain the cornerstone for patients with early-stage disease and represent the only option for potential cure in HCC. However, fewer than 10% of patients are considered suitable for surgery at the time of diagnosis. Locoregional therapies, defined as minimally invasive image-guided liver tumour-directed procedures, are integral to in the management of HCC. This review discusses the role of locoregional therapies in HCC management in the emergence of immune and systemic treatments.