Open AccessDrug Compatibility in Treatment of Chronic Infectious Diseases
Author(s) -
Е. С. Базрова,
Г. Д. Каминский,
Л. Ю. Ильченко,
А. Матин,
И. Г. Никитин
Publication year - 2021
Publication title -
arhivʺ vnutrennej mediciny
Language(s) - English
Resource type - Journals
eISSN - 2411-6564
pISSN - 2226-6704
DOI - 10.20514/2226-6704-2021-11-5-344-358
Subject(s) - pharmacotherapy , polypharmacy , drug , medicine , intensive care medicine , pharmacology , adverse effect , regimen
The article considers the features of pharmacotherapy of patients with chronic infectious diseases and co-morbidities in conditions of polypharmacy, the principles of drug metabolism, variants of adverse effects and drug-drug interactions, the possibilities of effective drug combinations. The purpose is to substantiate the possibility and emphasize the relevance of the additional search of the creation of the most optimal combinations of drugs for long-term and massive pharmacotherapy, that could be due to a beneficial drug-drug interaction, optimization of the regimen, route of drug administration and multitarget of the therapeutic effect, reduce the pharmacological load while maintaining the effectiveness of the treatment, increase patient adherence to drug therapy.