Open AccessFormulation and Evaluation of Hydro-gel containing Eclipta alba extract
Author(s) -
Pushpendra Kumar Kurre,
Suresh Kumar Ghritlahare,
Manmohan Singh Jangdey
Publication year - 2020
Publication title -
pharmaceutical and biosciences journal
Language(s) - English
Resource type - Journals
ISSN - 2582-0540
DOI - 10.20510/ukjpb/8/i5/1606402614
Subject(s) - skin irritation , irritation , traditional medicine , antifungal , chemistry , swelling , rheology , gum acacia , chromatography , food science , materials science , medicine , dermatology , composite material , immunology
Formulation & evaluation of Eclipta alba hydro-gel, the medicinal herbal hydrogel was prepared by using alcoholic extracted leaf powder of Eclipta alba, Carbopol-934, Acacia, Glycerin Sodium benzoate and HPMC. Leaves in concentration (1% and 5%) and evaluated using physiological measurements. The prepared herbal hydrogel formulation was studied for pre-liminary evaluation such as Viscosity, pH, Spreadibility, Rheological studies, Skin irritation test and Drug content uniformity Accelerated stability studies for 3 months. The Formulated hydrogel pH was found to range of 6.45 to 6.68, which lies in the normal pH range of the skin. The formulations did not produce any skin irritation, i.e., erythematic and edema for about a week, when applied over the skin. The viscosity of formulation was range 1024 which spread on the skin properly. On the basis of evaluation study, it can be concluded that Eclipta alba Linn. Medicinal herbal hydrogel may be used for wound healing, antibacterial and antifungal activity anticancer, Anti-inflammatory activity.