Open AccessEFFECT OF RED MULBERRY JUICE (MORUS RUBRA) ON THE INFLAMMATORY RESPONSE IN MALE WISTAR RATS DUE TO EXPOSURE TO CIGARETTE SMOKE
Author(s) -
Rivan Virlando Suryadinata,
Merryana Adriani,
Stefani Cornelia Sardjono
Publication year - 2021
Publication title -
media gizi indonesia/media gizi indonesia
Language(s) - English
Resource type - Journals
eISSN - 2540-8410
pISSN - 1693-7228
DOI - 10.20473/mgi.v16i3.233-237
Subject(s) - cigarette smoke , smoke , respiratory tract , immune system , positive control , inflammatory response , physiology , medicine , chemistry , toxicology , traditional medicine , respiratory system , immunology , inflammation , biology , organic chemistry
The increasing number of tobacco users will directly impact to an increase in the number of passive smokers. Various harmful substances that enter the respiratory tract can cause health problems. The airway will recognize these substances as pathogen and activate immune response accordingly. Inammatory response becomes one of the eects of body compensation due to an increased pathogen. This eect is indicated by the elevation of C-Reactive Protein as one systemic inammatory response parameters in the body. This study aimed to determine the ecacy of red mulberry juice to reduce levels of C-Reactive Protein in Wistar rats because exposure to cigarette smoke. This is an experimental study with a post-test control group design. Animals were divided into negative control group, positive control group, and 3 treatment groups with dierent red mulberry doses. The positive control group showed the highest increase in C-Reactive Protein levels compared with the red mulberry intake group (p<0,001). In conclusion, the administration of red mulberry juice can reduce inammatory response in rats because of exposure to cigarette smoke.