Open AccessJUS SEMANGKA MENURUNKAN NEUTROFIL TIKUS JANTAN GALUR WISTAR YANG TERPAPAR ASAP ROKOK
Author(s) -
Rizky Prihandari,
Lailatul Muniroh
Publication year - 2018
Publication title -
media gizi indonesia/media gizi indonesia
Language(s) - English
Resource type - Journals
eISSN - 2540-8410
pISSN - 1693-7228
DOI - 10.20473/mgi.v11i2.166-174
Subject(s) - cigarette smoke , analysis of variance , placebo , medicine , significant difference , zoology , traditional medicine , chemistry , toxicology , biology , pathology , alternative medicine
Cigarette smoke contains many hazardous substances and free radical which affect respiratory system. Watermelon “Sugar Baby” juice contain lycopene as antiin ammation. The aim of this research was to analyze the effect of watermelon as antiin ammation toward neutrophils count in wistar strain male rats exposed by cigarette smoke. This study was an experimental laboratory research with pre and post test control group design. Sample consisted of 24 wistar strain male rats with ±150-230 grams weight and 3 months old which were divided into four groups. Control group was given placebo (aquadest) and treatment groups were given w atermelon juice with terraced quantity (1.5 ml, 2.5 ml, and 3.5 ml). Every group was given two sticks of cigarette smoked per day during two weeks then smoked with treatment during one week. Neutrophil from peripheral smear was observed by manual method and statistically analyzed using Anova Mixed Design and continued with One Way Anova. The result showed signi cant increased of neutrophil at second observation on control group (p=0.002) and treatment groups (p=0.000). Signi cance decreased also found in the treatment groups’s at third observation p=0.000. Signi cant between each group p= 0.017. There was signi cant different between control and treatment groups but there was no signi cant different between each treatment groups. This study concluded that there was decreased of neutrophil in wistar strain male rats which were given w atermelon juice 1.5 ml, 2.5 ml, and 3.5 ml during in ammation. 3.5 ml w atermelon juice which were given showed better result as antiin ammation..