
Biomarker Pernapasan pada Penyakit Paru
Author(s) -
Novita Maulidiyah,
Muhammad Amin
Publication year - 2019
Publication title -
jurnal respirasi
Language(s) - English
Resource type - Journals
eISSN - 2621-8372
pISSN - 2407-0831
DOI - 10.20473/jr.v1-i.2.2015.67-71
Subject(s) - breath gas analysis , medicine , copd , biomarker , exhaled breath condensate , lung cancer , cystic fibrosis , pulmonary disease , exhalation , asthma , pathology , intensive care medicine , anesthesia , chemistry , biochemistry , anatomy
Breath analysis provides a convenient and simple alternative to traditional specimen testing in clinical laboratory diagnosis. As such, substantial research has been devoted to the analysis and identification of breath biomarkers. Development of new analytes enhances the desirability of breath analysis especially for patients who monitor daily biochemical parameters. Elucidating the physiologic significance of volatile substances in breath is essential for clinical use. This review describes the use of breath biomarkers in diagnosis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), lung cancer, as well as other pulmonary diseases. A number of breath biomarkers in lung pathophysiology will be described including nitric oxide (NO), carbon monoxide (CO), hydrogen peroxide (H2O2) and other hydrocarbons.