Open AccessThe Anthelmintic Activity Of Etanol Extract of Porang Tubers Against Fasciola gigantica In Vitro
Author(s) -
Firanda Agustina,
Rochmah Kurnijasanti,
Lucia Tri Suwanti,
Nunuk Dyah Retno Lastuti,
Kadek Rachmawati,
Lilik Maslachah
Publication year - 2021
Publication title -
journal of basic medical veterinary
Language(s) - English
Resource type - Journals
ISSN - 2774-9959
DOI - 10.20473/jbmv.v10i2.31235
Subject(s) - anthelmintic , fasciola gigantica , albendazole , traditional medicine , in vitro , biology , chemistry , helminths , medicine , immunology , biochemistry , ecology
This study aims to determine the anthelmintic activity ethanol extract of porang tubers (A. oncophillus) against F. gigantica worms in vitro. There were five treatments and each treatment was done in five replications and used 10 F. gigantica. The treatments of this research were K- with CMC Na 1%, K+ with Albendazole 2.4 mg/ml, P1 with extract concentration 5%, P2 with extract concentration 10%, P3 with extract concentration 20%. The results showed that the extract of Porang tuber (A. oncophillus) had an anthelmintic effect against F. gigantica worms in vitro. In the extract with a concentration of 20%, there were anthelmintic properties that almost the same as Albendazole. The higher the extract concentration, the higher the anthelmintic properties. The longer the immersion time, the higher the number of dead worms. The morphological changes was evaluated by light microscopic examination and the results showed many histopathological changes on the morphology of F. gigantica. The results indicate that the possible use of the tubers as a potential anthelmintic against F. gigantica.