Open AccessThe Effectiveness of Curcuma zedoaria Extract in Enhancing Non Spesific Immune Responses of Tiger Grouper (Epinephelus fuscoguttatus)
Author(s) -
Agus Putra Abdul Samad,
Eva Ayuzar,
Ilhamdi Ilhamdi,
Muhammad Hatta
Publication year - 2021
Publication title -
journal of aquaculture and fish health/journal of aquaculture and fish health
Language(s) - English
Resource type - Journals
eISSN - 2528-0864
pISSN - 2301-7309
DOI - 10.20473/jafh.v11i1.27530
Subject(s) - grouper , immunostimulant , biology , curcuma , epinephelus , immune system , respiratory burst , fishery , food science , traditional medicine , botany , immunology , fish <actinopterygii> , medicine
The present study was conducted to determine the effect of using turmeric extract (Curcuma zedoaria) on non specific immune of grouper (Epinephelus fuscoguttatus). During the study, fish were fed a diet containing 0, 0.5, 1.0, 2.5 g extract/kg feed twice a day for 14 days. Observations of non-specific immune parameters such as respiratory burst activity, chemiluminescent response, phagocytic activity, superoxidase dismutase (SOD) and lysozyme activity were sampled at 0, 1, 2, 4, 7 and 14 days. The results showed that fish fed C. zedoaria with 0.5 g/kg feed affected non-specific immune responses, and showed significant effect in the short term. On contrary, for long-term administration causes a decrease and inhibition of non-specific cellular defense activity. Thus, this study concluded that the administration of turmeric extract added to the feed can act as an immunostimulant and increase the non-specific immune response in grouper (E. fuscoguttatus).