Potential role of exercise-induced glucose-6-phosphate isomerase in skeletal muscle function | Zendy

Seong Eun Kwak | Zendy; Hyung Eun Shin | Zendy; Di Di Zhang | Zendy; Jihyun Lee | Zendy; Kyung Jin Yoon | Zendy; Jun Hyun Bae | Zendy; Hyo Youl Moon | Zendy; Wook Song | Zendy

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Potential role of exercise-induced glucose-6-phosphate isomerase in skeletal muscle function

Author(s) -

Seong Eun Kwak,

Hyung Eun Shin,

Di Di Zhang,

Jihyun Lee,

Kyung Jin Yoon,

Jun Hyun Bae,

Hyo Youl Moon,

Wook Song

Publication year - 2019

Publication title -

physical activity and nutrition

Language(s) - English

Resource type - Journals

eISSN - 2233-6842

pISSN - 2233-6834

DOI - 10.20463/jenb.2019.0014

Subject(s) - skeletal muscle , function (biology) , glucose 6 phosphate , isomerase , phosphate , chemistry , medicine , endocrinology , biochemistry , microbiology and biotechnology , biology , enzyme

Recent studies have shown that glucose-6-phosphate isomerase (GPI)-which is a glycolysis interconversion enzyme-reduces oxidative stress. However, these studies are limited to tumors such as fibrosarcoma, and there are no studies that have examined the effects of exercise on GPI expression in mice skeletal muscle. Furthermore, GPI acts in an autocrine manner thorough its receptor, autocrine motility factor receptor (AMFR); therefore, we investigated expression level changes of secreted GPI from skeletal muscle in in vitro study to examine the potential role of GPI on skeletal muscle.

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