Resistance training increases fibroblast growth factor-21 and irisin levels in the skeletal muscle of Zucker diabetic fatty rats | Zendy

Hee-jae Kim | Zendy; Wook Song | Zendy

Open Access

Resistance training increases fibroblast growth factor-21 and irisin levels in the skeletal muscle of Zucker diabetic fatty rats

Author(s) -

Hee-jae Kim,

Wook Song

Publication year - 2017

Publication title -

physical activity and nutrition

Language(s) - English

Resource type - Journals

eISSN - 2233-6842

pISSN - 2233-6834

DOI - 10.20463/jenb.2017.0008

Subject(s) - skeletal muscle , fgf21 , endocrinology , medicine , resistance training , insulin resistance , myokine , fibroblast growth factor , chemistry , diabetes mellitus , receptor

Although the fibroblast growth factor-21 (FGF-21) and irisin roles are well demonstrated in metabolic disease, there have been no reports investigating the effect of resistance exercise on FGF-21 and irisin levels in diabetic skeletal muscles. Therefore, this study aimed to investigate the change of FGF-21 and irisin levels in various skeletal muscles, and their association with muscle strength, following 8 weeks of resistance training using Zucker diabetic fatty rats (type 2 diabetic animal models).

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