Open AccessEffects of creatine monohydrate supplementation and exercise on depression-like behaviors and raphe 5-HT neurons in mice
Author(s) -
Na-Ri Ahn,
Yea Hyun Leem,
Morimasa Kato,
Hyukki Chang
Publication year - 2016
Publication title -
physical activity and nutrition
Language(s) - English
Resource type - Journals
eISSN - 2233-6842
pISSN - 2233-6834
DOI - 10.20463/jenb.2016.09.20.3.4
Subject(s) - raphe , depression (economics) , creatine , medicine , endocrinology , serotonin , receptor , serotonergic , economics , macroeconomics
The effects of creatine and exercise on chronic stress-induced depression are unclear. In the present study, we identified the effects of 4-week supplementation of creatine monohydrate and/or exercise on antidepressant behavior and raphe 5-HT expression in a chronic mild stress-induced depressed mouse model.
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