Jakyakgamcho-tang and Its Major Component, Paeonia Lactiflora, Exhibit Potent Anti-glycation Properties | Zendy

Junghyun Kim | Zendy; ChanSik Kim | Zendy; Young Sook Kim | Zendy; Ik Soo Lee | Zendy; Jin Sook Kim | Zendy

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Jakyakgamcho-tang and Its Major Component, Paeonia Lactiflora, Exhibit Potent Anti-glycation Properties

Author(s) -

Junghyun Kim,

ChanSik Kim,

Young Sook Kim,

Ik Soo Lee,

Jin Sook Kim

Publication year - 2016

Publication title -

physical activity and nutrition

Language(s) - English

Resource type - Journals

eISSN - 2233-6842

pISSN - 2233-6834

DOI - 10.20463/jenb.2016.0049

Subject(s) - paeonia lactiflora , glycation , paeoniflorin , traditional medicine , chemistry , component (thermodynamics) , chromatography , medicine , biochemistry , high performance liquid chromatography , physics , receptor , alternative medicine , pathology , thermodynamics

Advanced glycation end products (AGEs) have been implicated in the pathogenesis of diabetes and other age-related diseases. AGE inhibitors or breakers, such as aminoguanidine and alagebrium, have been proposed as therapeutic agents for AGE-related disorders. Jakyakgamcho-tang (JGT) is a well-known traditional herbal formula, which consists of the radix of Paeonia lactiflora Pallas (PR) and the radix and rhizome of Glycyrrhiza uralensis Fisch (GR). The purpose of this study was to evaluate the inhibitory and breaking activities of JGT, PR, and GR against AGEs.

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