Green synthesis of 2-aryl-4-phenyl-quınazolıne derıvatives promoted by lactıc acıd | Zendy

Belgheis Adrom | Zendy; Nourallah Hazeri | Zendy; Malek Taher Maghsoodlou | Zendy; Mojtaba Lashkari | Zendy; Maryam Fatahpour | Zendy

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Green synthesis of 2-aryl-4-phenyl-quınazolıne derıvatives promoted by lactıc acıd

Author(s) -

Belgheis Adrom,

Nourallah Hazeri,

Malek Taher Maghsoodlou,

Mojtaba Lashkari,

Maryam Fatahpour

Publication year - 2017

Publication title -

macedonian journal of chemistry and chemical engineering

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.19

H-Index - 16

eISSN - 1857-5625

pISSN - 1857-5552

DOI - 10.20450/mjcce.2017.1137

Subject(s) - aryl , ammonium acetate , chemistry , solvent , reaction conditions , organic chemistry , green chemistry , lactic acid , environmentally friendly , aldehyde , catalysis , nuclear chemistry , reaction mechanism , alkyl , high performance liquid chromatography , biology , bacteria , genetics , ecology

An environmentally benign three-component synthetic method is described for the construction of 2-aryl-4-phenylquinazoline derivatives from the reaction between aldehydes, ammonium acetate, and 2-aminobenzophenone in the presence of lactic acid in a solvent-less media. The benefits of the reaction were good yields, a simple procedure, simple starting materials short reaction time, easy work-up, and cleaner reaction profiles.

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