Open AccessAn ACE2-IgG4 Fc Fusion Protein Demonstrates Strong Binding to All Tested SARS-CoV-2 Variants and Reduced Lung Inflammation in Animal Models of SARS-CoV-2 and Influenza
Author(s) -
Emmanuel Y. Mérigeon,
Dong Yang,
Elizabeth Ihms,
Leda Bassit,
Elizabeth Fitzpatrick,
Colleen B. Jonsson,
Raymond F. Schinazi,
David S. Block,
Henrik S. Olsen
Publication year - 2022
Publication title -
pathogens and immunity
Language(s) - English
Resource type - Journals
ISSN - 2469-2964
DOI - 10.20411/pai.v7i1.491
Subject(s) - neutralization , antibody , neonatal fc receptor , in vivo , vero cell , pharmacokinetics , fusion protein , receptor , inflammation , virus , fragment crystallizable region , virology , biology , pharmacology , immunoglobulin g , immunology , recombinant dna , biochemistry , gene , microbiology and biotechnology