Lack of Atorvastatin Effect on Monocyte Gene Expression and Inflammatory Markers in HIV-1- infected ART-suppressed Individuals at Risk of non-AIDS Comorbidities | Zendy

Anjana Yadav | Zendy; Andrew V. Kossenkov | Zendy; Louise C. Showe | Zendy; Sarah J. Ratcliffe | Zendy; Grace Choi | Zendy; Luis J. Montaner | Zendy; Pablo Tebas | Zendy; Pamela A. Shaw | Zendy; Ronald G. Collman | Zendy

Open Access

Lack of Atorvastatin Effect on Monocyte Gene Expression and Inflammatory Markers in HIV-1- infected ART-suppressed Individuals at Risk of non-AIDS Comorbidities

Author(s) -

Anjana Yadav,

Andrew V. Kossenkov,

Louise C. Showe,

Sarah J. Ratcliffe,

Grace Choi,

Luis J. Montaner,

Pablo Tebas,

Pamela A. Shaw,

Ronald G. Collman

Publication year - 2021

Publication title -

pathogens and immunity

Language(s) - English

Resource type - Journals

ISSN - 2469-2964

DOI - 10.20411/pai.v6i2.461

Subject(s) - cd14 , atorvastatin , monocyte , medicine , ccr2 , cd16 , immunology , cd163 , ccl2 , inflammation , flow cytometry , chemokine , biology , macrophage , immune system , in vitro , cd8 , biochemistry , cd3 , chemokine receptor

Many people living with HIV have persistent monocyte activation despite viral suppression by antiretroviral therapy (ART), which contributes to non-AIDS complications including neurocognitive and other disorders. Statins have immunomodulatory properties that might be beneficial by reducing monocyte activation.

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