Open AccessClinical efficacy of a cosmetic formulation with vitamin B3 for the treatment of oily skin
Author(s) -
Marcella Gabarra Almeida Leite,
Patrícia Maria Berardo Gonçalves Maia Campos
Publication year - 2022
Publication title -
jornal de investigação biomédica e biofarmacêutica/jornal de investigação biomédica e biofarmacêutica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.129
H-Index - 1
eISSN - 2182-2379
pISSN - 2182-2360
DOI - 10.19277/bbr.18.2.273
Subject(s) - transepidermal water loss , acne , cosmetics , skin care , medicine , dermatology , dry skin , stratum corneum , vitamin , context (archaeology) , sensitive skin , niacinamide , chemistry , pathology , paleontology , biochemistry , nicotinamide , nursing , biology , enzyme
Oily skin has special needs, as the treatment and prevention of non-inflammatory acne and sebum control, maintaining skin barrier function and hydration. In this context, the importance of the development of specific and innovative cosmetics formulations to to fulfill the needs of this type of skin is evident. In this view, the aim of this study was the evaluation of the clinical efficacy of a cosmetic formulation containing Vitamin B3 in the treatment of oily skin using biophysical and skin imaging techniques. Female volunteers (n=40) between 18 to 30 years old with oily skin and/or mild inflammatory acne were recruited and received a formulation containing, or not (vehicle), 3% of Vitamin B3. Stratum corneum water content, transepidermal water loss (TEWL), sebum content and quantity of porphyrins were analyzed before (baseline) and after 28 days of application. Finally, an efficacy perception questionnaire was applied at the study end. The formulation with vitamin B3, showed a significant reduction of sebum and porphyrin content. The study participants in the assessment of perceived efficacy also reported these results. The studied formulation with Vitamin B3 was effective for oily skin care, acting on important parameters, such as controlling oiliness and improving skin appearance. Keywords: cosmetics, Niacinamide, skin physiology, oily skin, biophysical and skin imaging