Open AccessOne-step Selective Synthesis of 13-epi-manoyl Oxide
Author(s) -
Olga Morarescu,
Marionela Traistari,
Alic Barbă,
Gheorghe Duca,
Nicon Ungur,
Veaceslav Kulciţki
Publication year - 2021
Publication title -
chemistry journal of moldova
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.275
H-Index - 5
eISSN - 2345-1688
pISSN - 1857-1727
DOI - 10.19261/cjm.2021.820
Subject(s) - chemistry , oxide , stereochemistry , organic chemistry
The selective one-step synthesis of 13-epi-manoyl oxide is reported based on a low-temperature superacidic cyclization of sclareol. The reaction conditions have been finely tuned in order to achieve a 9:1 ratio between epimeric oxides in favor of the desired 13-epi-oxide.