Open AccessImplications of Global and Local Mobility in Amorphous Excipients as Determined by DSC and TM DSC
Author(s) -
Ion Dranca,
Tudor Lupaşcu
Publication year - 2009
Publication title -
chemistry journal of moldova
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.275
H-Index - 5
eISSN - 2345-1688
pISSN - 1857-1727
DOI - 10.19261/cjm.2009.04(2).02
Subject(s) - differential scanning calorimetry , amorphous solid , chemistry , annealing (glass) , heat capacity , glass transition , calorimetry , analytical chemistry (journal) , materials science , crystallography , polymer , thermodynamics , chromatography , organic chemistry , composite material , physics
The paper explores the use of differential scanning calorimetry (DSC) and temperature modulated differential scanning calorimetry (TM DSC) to study α- and β- processes in amorphous sucrose and trehalose. The real part of the complex heat capacity is evaluated at the frequencies, f, from 5 to 20mHz. β-relaxations were studied by annealing glassy samples at different temperatures and subsequently heating at different rates in a differential scanning calorimeter.