Open AccessTARGETED DRUG DELIVERY SYSTEMS IN BREAST CANCER CHEMOTHERAPY
Author(s) -
A. H. Al-Humairi,
Olga Ostrovsky,
Е. В. Зыкова,
Д. Л. Сперанский
Publication year - 2021
Publication title -
vestnik volgogradskogo gosudarstvennogo medicinskogo universiteta
Language(s) - English
Resource type - Journals
eISSN - 1994-9499
pISSN - 1994-9480
DOI - 10.19163/1994-9480-2021-1(77)-12-16
Subject(s) - drug delivery , breast cancer , targeted drug delivery , drug , medicine , cancer , clinical trial , nanotechnology , liposome , pharmacology , materials science
The article presents a review, systematizing the state and directions of development in the fabrication of targeted drug delivery systems in relation to the treatment of breast cancer. Drug delivery systems constructed on the basis of natural and artificial liposomes, nanoparticles of various nature, polymers, and dendrimer structures are consistently considered. For each class of platforms, information is provided on the features of the structure and functional properties of carriers, on successful examples of their use for the treatment of breast cancer at various stages of preclinical and clinical trials. The most probable directions to achieve a progress in the development of new systems for targeted delivery of antitumor drugs are shown.