Open AccessHEPARAN SULFATES EXPRESSION IN SURGERY MATERIAL OF OVARIAN ENDOMETRIAL CYSTS
Author(s) -
С. В. Айдагулова,
Yu. S. Timofeeva,
А.V. Volchek,
В. М. Кулешов,
И. О. Маринкин
Publication year - 2020
Publication title -
vestnik volgogradskogo gosudarstvennogo medicinskogo universiteta
Language(s) - English
Resource type - Journals
eISSN - 1994-9499
pISSN - 1994-9480
DOI - 10.19163/1994-9480-2020-4(76)-96-99
Subject(s) - heparan sulfate , endometriosis , immunohistochemistry , pathogenesis , perlecan , pathological , endometrium , medicine , chemistry , cancer research , glycosaminoglycan , pathology , microbiology and biotechnology , biology , biochemistry
The expression of heparan sulfate proteoglycans in eutopic and heterotopic endometrium in patients with ovarian endometriosis was studied using the method of immunohistochemistry. The simultaneous increase in the level of expression of core proteins of all studied heparan sulfate proteoglycans and the content of heparan sulfate in pathological tissues indicates the important role of glycosylated molecules in the pathogenesis of ovarian endometriosis.