Open AccessDYNAMICS OF RAT SKIN FORMATION DURING THE TRANSITION FROM PRENATAL TO EARLY POSTNATAL ONTOGENESIS
Author(s) -
Е. С. Мишина,
М.А. Затолокина,
Е.С. Затолокина
Publication year - 2020
Publication title -
vestnik volgogradskogo gosudarstvennogo medicinskogo universiteta
Language(s) - English
Resource type - Journals
eISSN - 1994-9499
pISSN - 1994-9480
DOI - 10.19163/1994-9480-2020-4(76)-77-80
Subject(s) - thickening , stratum corneum , ontogeny , dermis , epidermis (zoology) , anatomy , biology , skin barrier , pathology , chemistry , medicine , endocrinology , dermatology , polymer science
The peculiarities of the skin formation as an organ are the basic knowledge for studying the aging and regeneration process. During studying this issue it is necessary to take into account the exogenous factors affecting the skin, which, in turn, is a "barrier organ". The study was carried out on the skin of male Wistar rats in the late prenatal and early postnatal periods. At the initial stages of its formation, the skin undergoes its morphofunctional changes such as thickening of the epidermis and the appearance of the stratum corneum, as well as thickening of the dermis and changes in the collagen fibers shape that make up its structure. The formation of the skin as a full-fledged "barrier organ" occurs in early postnatal ontogenesis.