Open AccessFEATURES OF THE DAILY PROFILE OF ARTERIAL PRESSURE AND THE POSSIBILITY OF DOCLINE DIAGNOSTICS OF ARTERIAL HYPERTENSION IN CHILDREN WITH TYPE 1 DIABETES
Author(s) -
N. V. Malyuzhinskaya,
К. В. Степаненко,
O. V. Polyakova,
Г. В. Клиточенко,
S.A. Emelyanova,
О В Новикова
Publication year - 2020
Publication title -
vestnik volgogradskogo gosudarstvennogo medicinskogo universiteta
Language(s) - English
Resource type - Journals
eISSN - 1994-9499
pISSN - 1994-9480
DOI - 10.19163/1994-9480-2020-3(75)-75-78
Subject(s) - medicine , diabetic nephropathy , blood pressure , diabetes mellitus , nephropathy , type 2 diabetes , cardiology , microcirculation , prospective cohort study , intensive care medicine , endocrinology
Diabetic nephropathy takes a leading place among diseases requiring replacement therapy for renal failure, and is also a leading cause of disability and mortality among patients with type 1 diabetes. The development of arterial hypertension is one of the markers of the formation of diabetic nephropathy. We performed a prospective cohort study. A comprehensive clinical and instrumental examination of 78 children with type 1 diabetes was carried out. The features of changes in the daily profile of blood pressure and microcirculatory disorders in children before the formation of diabetic nephropathy were revealed. A mathematical model is developed for predicting the development of arterial hypertension by determining microcirculation parameters using a laser Doppler flowmeter. Early diagnosis will allow timely prescribing of pathogenetic treatment, improving the prognosis of this category of patients.