Open AccessPharmacological therapy in critically ill patients with peripheral and concomitant arteriopathy
Author(s) -
Nicola Troisi,
Antonio Trani,
Pierluigi Cappiello
Publication year - 2018
Publication title -
aboutopen
Language(s) - English
Resource type - Journals
ISSN - 2465-2628
DOI - 10.19156/abtpn.2018.0068
Subject(s) - cilostazol , iloprost , medicine , critical limb ischemia , arterial disease , concomitant , peripheral , amputation , disease , cardiology , intensive care medicine , vascular disease , surgery , prostacyclin , aspirin
Peripheral arterial disease is one of the most frequent clinical manifestations of atherosclerotic disease. The clinical picture of critical ischemia of the lower limbs is often burdened by high mortality and the risk of limb amputation. The direct and indirect prostanoids, and in particular iloprost and cilostazol, are effective in the medical treatment of peripheral arterial disease. We describe here five clinical cases in which iloprost and cilostazol have been successfully administered in arterial patients with various concomitant cardiovascular diseases, highlighting a good safety profile in relation to the cardiocascular risk profile (Cardiology).