Complicated plantar ulcer in diabetic patient with multiple comorbidities

Diabetic foot syndrome is characterized by an intrinsic patient fragility and involves complex medical and surgical therapeutic approach. Lesions, often chronic, have a high risk of recurrence and amputation. The patient with diabetic foot is more frequently affected by comorbidities, not only for micro-angiopathic complications of diabetes mellitus but also for the frequent presence of cardiovascular disease. We report the case of a 63-year-old diabetic patient with multiple comorbidities. Treatment with linagliptin allowed to simplify the therapy for glycemic control, switching from a injective therapy four times daily to a therapy with only basal insulin and linagliptin. This therapy has proven to be safe and suitable to maintain good glycemic control even in a fragile patient with diabetic foot and middle-severe renal insufficiency of diabetic origin (Diabetology).