Open AccessMolecular Dynamics and MM-PBSA Studies for Deciphering Molecular Interactions of Valproic Acid with CYP2C9 Mutants F114L and I207T
Author(s) -
Ahmet Can Timuçin
Publication year - 2021
Publication title -
süleyman demirel üniversitesi fen bilimleri enstitüsü dergisi/süleyman demirel üniversitesi fen bilimleri enstitüsü dergisi
Language(s) - English
Resource type - Journals
eISSN - 1308-6529
pISSN - 1300-7688
DOI - 10.19113/sdufenbed.801973
Subject(s) - valproic acid , molecular mechanics , mutant , molecular dynamics , cytochrome p450 , chemistry , cyp2c9 , amino acid , wild type , biochemistry , pharmacology , biology , enzyme , computational chemistry , gene , neuroscience , epilepsy