Open AccessThe Role of Apoptotic Factors in Assessing Progression of Periodontal Disease
Author(s) -
Darya Dabiri,
Sindhu Halubai,
Mary Layher,
Christine P. Klausner,
Huwaida Makhoul,
Lin Gui,
G. Eckert,
Heba Abuhussein,
Pachiyappan Kamarajan,
Yvonne L. Kapila
Publication year - 2016
Publication title -
international journal of dentistry and oral science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.105
H-Index - 2
ISSN - 2377-8075
DOI - 10.19070/2377-8075-1600064
Subject(s) - apoptosis , fas ligand , dna fragmentation , medicine , periodontitis , saliva , gastroenterology , immunology , pathology , oncology , biology , programmed cell death , biochemistry
The mechanisms responsible for periodontal disease progression remain unclear. However, recent studies suggest that apoptosis may be one mechanism underlying the pathophysiology of periodontal disease progression. This pilot study is the 3 month follow-up of our published baseline study on the presence of apoptotic factors in serum, saliva, and gingival crevicular fluid (GCF) and their association with periodontal disease severity and activity.