Open AccessEffect of hydro-methanol stem extract from Anacardium occidentale on haematology and serum biochemistry in cockerels
Author(s) -
Jacinta Ngozi Omeke,
Ugochukwu Iniobong Chukwuebuka Ikenna,
Emejuo Nnenna Tochi,
Iheodioh John Ikechukwu,
Anaga Aruh Ottah,
Ezema Wilfred Sunday,
J. O. A. Okoye
Publication year - 2021
Publication title -
revista de medicina veterinaria/revista medicina veterinaria
Language(s) - English
Resource type - Journals
eISSN - 2389-8526
pISSN - 0122-9354
DOI - 10.19052/mv.vol1.iss42.10
Subject(s) - uric acid , creatinine , hematology , medicine , alanine aminotransferase , biology , zoology , endocrinology
This study aims to investigate the effects of orally administered graded doses of hydro-methanol stem extract from Anacardium occidentale (MSEAO) on the haematology and serum biochemistry of chickens. Forty, 8-weeks old cockerel chickens were randomly assigned into four groups (groups 1, 2, 3 and 4) of ten birds each. Groups 1, 2 and 3 received 3000, 1500 and 500 mg/kg body weight of MSEAO, respectively, while chickens in control group (group 4) were given drinking water placebo. Blood samples were collected from all chickens on day 0- and 48-hours post-treatment. Haematology and serum biochemistry were evaluated following standard procedures. The results showed that most of the haematological parameters in the treated groups did not differ significantly as compared to the control group. The serum biochemistry results showed that the serum alanine aminotransferase (ALT) activity ingroups 1 and 2 were significantly (P 0.05) lower than that ingroups 3 and 4. Serum uric acid levels ingroups 1 and 2 chickens were significantly (P 0.05) lower than that in the control group, while the creatinine levels of chickens in the treated groups were significantly (P 0.05) lower than that of chickens in the control group. It was concluded that MSEAO, as used in the study, led to significant changes in heterophil counts, serum ALT and ALP activities, uric acid, creatinine, and calcium levels