Open AccessPOLYMORPHISM OF SEVEN MICROSATELLITE STR-LOCI INCLUDED IN THE STANDARD SET CODIS, ESS AND ISSOL FOR THE NATIVE POPULATION OF THE REPUBLIC OF ARMENIA
Author(s) -
M. S. Bisharyan,
D. N. Arutyunyan,
M. R. Bagdasaryan,
A. L. Sargsyan
Publication year - 2019
Publication title -
sudebnaâ medicina
Language(s) - English
Resource type - Journals
eISSN - 2411-8729
pISSN - 2409-4161
DOI - 10.19048/2411-8729-2019-5-1-25-28
Subject(s) - microsatellite , genetics , population , allele frequency , biology , armenian , allele , demography , history , gene , ancient history , sociology
The aim of the work was to study polymorphism of microsatellite STR loci vWA, CSF1PO, TPOX, TH01, D16S539, D13S317, D7S820 included in CODIS, ESS and ISSOL standard core loci for Armenian population. Correspondence of frequencies of examined loci to the Hardy – Weinberg equilibrium was revealed. To distinguish genetic variability of STR loci we examined vWA, CSF1PO, TPOX, TH01, D16S539, D13S317, D7S820STR loci of Armenian population residing in the territory of Armenia and compared with data of Caucasian-American population presented in the Promega Technical Manual Allele Frequencies for Caucasian-Americans protocol. This comparative study revealed significant differences for tested populations. The results indicate that this set of polymorphic STR loci provides some polymorphic information. Therefore, prior to the usage of new DNA markers included in CODIS, ESS and ISSOL standard core loci into forensic casework, as well as DNA paternity and relationship testing, studies should be performed on Armenian populationto establish polymorphism of microsatellite STR loci specific for Armenian population.